Search Results - central nervous system (cns)

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Synthetic engineered potassium channel (EKC) for gene therapy
Available For: Licensing<h2>Summary</h2>{{start}} Epilepsy affects around 60 million people globally and there remains an urgent need for novel treatment methods. Researchers at UCL Institute of Neurology have developed a novel synthetic engineered potassium channel (EKC) as a gene therapy tool to treat epilepsy and other neurological c...
Published: 20/06/2017   |   Inventor(s): Stephanie Schorge, Albert Snowball, Elodie Chabrol, Dimitri Kullmann, Matthew Walker
Keywords(s): Central Nervous System (CNS)
Category(s): Gene/Cell Therapy
Tau-gene-specific non-coding RNA genes for the therapeutic reduction of tau levels
Available for: Exclusive/Non-Exclusive licensing<h2>Summary</h2>{{start}} During genome transcription, both coding and non-coding transcripts are generated with a wide range of both size and coding potential. Among these are long non-coding RNA (lncRNA) genome transcripts, some of which are antisense to protein-coding genes (AS-lncRNAs)...
Published: 02/06/2017   |   Inventor(s): Rohan de Silva, Roberto Simone
Keywords(s): Central Nervous System (CNS)
Category(s): Therapeutic
Drusen Diagnostic
Available for: Exclusive/Non-exclusive licensing<h2>Summary</h2>{{start}} AMD is the most common cause of irreversible vision impairment in the Western world. There is currently no cure for AMD and all the efforts concentrate on managing symptoms and early detection and treatment of AMD significantly reduces vision impairment. Most pati...
Published: 11/12/2015   |   Inventor(s): Imre Lengyel, Richard Thompson, Jane Flinn
Keywords(s): Central Nervous System (CNS), Ophthalmology & Optometry
Category(s): Antibodies & Binding Agents, Diagnostic/Prognostic, Imaging - Medical
Drug Delivery System for Crossing the Blood Brain or Blood Retinal Barrier (UDDS)
Available For: Exclusive licensing<h2>Summary</h2>{{start}} The blood retinal barrier (BRB), and the blood brain barrier (BBB), represent a significant impediment to drug delivery to the eye and the brain, respectively. This lack of drug penetration has resulted in diseases, such as Age-related Macular Degeneration (AMD), Alzheimer's Di...
Published: 25/03/2015   |   Inventor(s): Francesca Cordeiro, Stephen Moss, Katy Coxon (now Dalchau), James Duggan
Keywords(s): Central Nervous System (CNS), Ophthalmology & Optometry
Category(s): Delivery of Drugs/Molecules, Regenerative Medicine
Early Diagnosis of Alzheimer's Disease
Available for: Exclusive Licensing/Non-exclusive Licensing<h2>Summary</h2>{{start}} Alzheimer Disease (AD) is the most common neurodegenerative disorder affecting half of all the people above 80 years of age. The available diagnostic methods are expensive and are not available to all patients. An easily detectable biomarker that could b...
Published: 25/03/2015   |   Inventor(s): Imre Lengyel, Tunde Peto
Keywords(s): Central Nervous System (CNS), Ophthalmology & Optometry
Category(s): Biomarkers, Diagnostic/Prognostic, Imaging - Medical
Voltage-Gated Sodium Channel Knockout Mice: Tools for Developing Therapeutics for the Treatment of Pain
Available for: Non-exclusive licensing<h2>Summary</h2>{{start}} Scientists at University College London have developed Voltage-Gated Sodium Channel subtype specific conditional knockout mice which provide invaluable tools for the development of therapeutics for the treatment of pain. {{end}}<h2>The Technology and its Advantages<...
Published: 01/03/2011   |   Inventor(s): John Wood
Keywords(s): Central Nervous System (CNS)
Category(s): Research Tools, Bioanalytics & Assays
Novel Method of Analysis of Stroke Data
Available For: Licensing<h2>Summary</h2>{{start}} Stroke is the leading cause of adult disability in the UK at an estimated overall annual cost of £7 billion. Clinical outcomes in stroke are not improving as fast as conditions of similar aetiology. A major cause is the difficulty in providing targeted care in a patient group with ...
Published: 28/07/2010   |   Inventor(s): Parashkev Nachev, Masud Husain, Geraint Rees
Keywords(s): Central Nervous System (CNS)
Category(s): Diagnostic/Prognostic
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