Search Results - central+nervous+system+(cns)

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Synthetic engineered potassium channel (EKC) for gene therapy

Available For: Licensing<h2>Summary</h2>{{start}} Epilepsy affects around 60 million people globally and there remains an urgent need for novel treatment methods. Researchers at UCL Institute of Neurology have developed a novel synthetic engineered potassium channel (EKC) as a gene therapy tool to treat epilepsy and other neurological conditions....

Published: 21/07/2022 | Inventor(s): Stephanie Schorge, Albert Snowball, Elodie Chabrol, Dimitri Kullmann, Matthew Walker

Keywords(s): Central Nervous System (CNS)

Category(s): Gene/Cell Therapy

Tau-gene-specific non-coding RNA genes for the therapeutic reduction of tau levels

Available for: Exclusive/Non-Exclusive licensing<h2>Summary</h2>{{start}} During genome transcription, both coding and non-coding transcripts are generated with a wide range of both size and coding potential. Among these are long non-coding RNA (lncRNA) genome transcripts, some of which are antisense to protein-coding genes (AS-lncRNAs)....

Published: 18/08/2017 | Inventor(s): Rohan De Silva, Roberto Simone

Keywords(s): Central Nervous System (CNS)

Category(s): Therapeutic

Drug Delivery System for Crossing the Blood Brain or Blood Retinal Barrier (UDDS)

Available For: Exclusive licensing<h2>Summary</h2>{{start}} The blood retinal barrier (BRB), and the blood brain barrier (BBB), represent a significant impediment to drug delivery to the eye and the brain, respectively. This lack of drug penetration has resulted in diseases, such as Age-related Macular Degeneration (AMD), Alzheimer's Disease...

Published: 30/01/2023 | Inventor(s): Francesca Cordeiro, Stephen Moss, Katy Coxon (now Dalchau), James Duggan

Keywords(s): Central Nervous System (CNS), Ophthalmology & Optometry

Category(s): Delivery of Drugs/Molecules, Regenerative Medicine

Voltage-Gated Sodium Channel Knockout Mice: Tools for Developing Therapeutics for the Treatment of Pain

Available for: Non-exclusive licensing<h2>Summary</h2>{{start}} Scientists at University College London have developed Voltage-Gated Sodium Channel subtype specific conditional knockout mice which provide invaluable tools for the development of therapeutics for the treatment of pain. {{end}}<h2>The Technology and its Advantages</h2>University...

Published: 17/08/2017 | Inventor(s): John Wood

Keywords(s): Central Nervous System (CNS)

Category(s): Research Tools, Bioanalytics & Assays