Search Results - ophthalmology & optometry

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Drusen Diagnostic
Available for: Exclusive/Non-exclusive licensing<h2>Summary</h2>{{start}} AMD is the most common cause of irreversible vision impairment in the Western world. There is currently no cure for AMD and all the efforts concentrate on managing symptoms and early detection and treatment of AMD significantly reduces vision impairment. Most pati...
Published: 11/12/2015   |   Inventor(s): Imre Lengyel, Richard Thompson, Jane Flinn
Keywords(s): Central Nervous System (CNS), Ophthalmology & Optometry
Category(s): Antibodies & Binding Agents, Diagnostic/Prognostic, Imaging - Medical
Lrg-1 antagonists: Direct effect upon cancer cells
Available for: Exclusive/Non-exclusive licensing<h2>Summary</h2>{{start}} The formation of new blood vessels by angiogenesis is a key feature of number of diseases including Age-related Macular Degeneration (AMD), Proliferative Diabetic Retinopathy (PDR), atherosclerosis, rheumatoid arthritis and cancer. Vascular Endothelial Growth Fact...
Published: 29/10/2015   |   Inventor(s): Stephen Moss, Xiaomeng Wang, John Greenwood
Keywords(s): Cancer, Ophthalmology & Optometry
Category(s): Antibodies & Binding Agents, Therapeutic
Drug Delivery System for Crossing the Blood Brain or Blood Retinal Barrier (UDDS)
Available For: Exclusive licensing<h2>Summary</h2>{{start}} The blood retinal barrier (BRB), and the blood brain barrier (BBB), represent a significant impediment to drug delivery to the eye and the brain, respectively. This lack of drug penetration has resulted in diseases, such as Age-related Macular Degeneration (AMD), Alzheimer's Di...
Published: 25/03/2015   |   Inventor(s): Francesca Cordeiro, Stephen Moss, Katy Coxon (now Dalchau), James Duggan
Keywords(s): Central Nervous System (CNS), Ophthalmology & Optometry
Category(s): Delivery of Drugs/Molecules, Regenerative Medicine
Early Diagnosis of Alzheimer's Disease
Available for: Exclusive Licensing/Non-exclusive Licensing<h2>Summary</h2>{{start}} Alzheimer Disease (AD) is the most common neurodegenerative disorder affecting half of all the people above 80 years of age. The available diagnostic methods are expensive and are not available to all patients. An easily detectable biomarker that could b...
Published: 25/03/2015   |   Inventor(s): Imre Lengyel, Tunde Peto
Keywords(s): Central Nervous System (CNS), Ophthalmology & Optometry
Category(s): Biomarkers, Diagnostic/Prognostic, Imaging - Medical
Treatment of fibrosis with ALDH inhibitors
Available for: Exclusive Licensing<h2>Summary</h2>{{start}} Fibrosis is the formation of excess fibrous connective tissue in response to injury and inflammation. If it happens in response to injury it is also referred to as scarring. Fibrosis is associated with conditions such as cystic fibrosis, cirrhosis, mucous membrane pemphigoid (M...
Published: 13/03/2015   |   Inventor(s): Virginia Calder, David Abraham, Sarah Dale
Keywords(s): Ophthalmology & Optometry
Category(s): Therapeutic
H4R antagonists for uveitis and other inflammatory diseases
Available For: Exclusive Licensing<h2>Summary</h2>{{start}} Histamine is a pleiotropic mediator involved in a variety of physiological processes including neurotransmission, endocrine and vascular processes. It also plays a key role in inflammation and binding to one of its four receptors (H1R-H4R). Researchers at UCL Institute of Opht...
Published: 12/03/2015   |   Inventor(s): Virginia Calder, Spyridon Chalkiadakis
Keywords(s): Ophthalmology & Optometry
Category(s): Therapeutic
Imatinib and other ABL inhibitors to treat ocular neovascularisation
Available for: Exclusive Licensing<h2>Summary</h2>{{start}} Retinal and choroidal diseases are the most common cause of vision loss in the western world. They are either caused by the leakage and neovasculatisation from retinal vessels (diabetic retinopathy, retinal vein occlusions, retinopathy of prematurity and neovascular glaucoma) o...
Published: 12/03/2015   |   Inventor(s): Christina Rhurberg
Keywords(s): Ophthalmology & Optometry
Category(s): Therapeutic
New genetic marker for Age-related Macular Degeneration (AMD)
Available for: Exclusive/Non-exclusive licensing<h2>Summary</h2>{{start}} AMD is the most common cause of irreversible vision impairment in the Western world and susceptibility to it is influenced by age, environmental and genetic factors. There is currently no cure for AMD and all the efforts concentrate on managing symptoms and early ...
Published: 02/03/2015   |   Inventor(s): John Yates, Valentina Cipriani, Tony Moore
Keywords(s): Ophthalmology & Optometry
Category(s): Bioinformatics, Biomarkers, Data Analysis, Diagnostic/Prognostic, Genomics, Proteomics & Pharmacogenomics
Dry Eye Diagnosis and Monitoring Software
Available For: Exclusive/Non-Exclusive/Option<h2>Summary</h2>{{start}} Clinicians at Moorfields Eye Hospital, the leading provider of eye health services in Europe have developed the first medical device which is able to quantify dry eye in a patient. The software quantifies the number, distribution and size of fluorescein staining all...
Published: 24/02/2015   |   Inventor(s): Anant Sharma, George Saleh
Keywords(s): Ophthalmology & Optometry
Category(s): Imaging - Medical, Software - Medical
Antibody Tablet for Occular Therapeutics Delivery
Available For: Exclusive licensing<h2>Summary</h2>{{start}}A novel solid formulation for the delivery of antibodies and protein therapeutics into the eye. This has several advantages over current methodologies which involve painful intraocular injections.{{end}}<h2>The Technology and its Advantages</h2>Antibody therapies are...
Published: 01/03/2011   |   Inventor(s): Peng Khaw, Steve Brocchini, Ashkan Khalili
Keywords(s): Ophthalmology & Optometry
Category(s): Delivery of Drugs/Molecules, Antibodies & Binding Agents
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