Search Results - therapeutic

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Neidle_Quadruplex-binding compounds - A novel anticancer strategy

Available For: Exclusive Licensing<h2>Summary</h2>{{start}} We have a first-in-class optimized small-molecule drug candidate ready for IND enabling studies with superior efficacy and activity against pancreatic cancer compared to existing agents, together with a distinct mechanism of action.{{end}}<h2>The Technology and its Advantages</h2>The...

Published: 18/09/2024 | Inventor(s): Stephen Neidle, Richard Angell, Sally Oxenford

Keywords(s): Cancer

Category(s): Therapeutic

Tau-gene-specific non-coding RNA genes for the therapeutic reduction of tau levels

Available for: Exclusive/Non-Exclusive licensing<h2>Summary</h2>{{start}} During genome transcription, both coding and non-coding transcripts are generated with a wide range of both size and coding potential. Among these are long non-coding RNA (lncRNA) genome transcripts, some of which are antisense to protein-coding genes (AS-lncRNAs)....

Published: 18/09/2024 | Inventor(s): Rohan De Silva, Roberto Simone

Keywords(s): Central Nervous System (CNS)

Category(s): Therapeutic

Formulations for the Prevention of Neural Tube Defects

Available for: License<h2>Summary</h2>{{start}} Exploring ways to prevent birth defects, researchers at the UCL Institute of Child Health have discovered novel supplements that if taken in pregnancy can reduce the chance of the baby having neural tube defects such as spina bifida or anencephaly. These are important in pregnancies where folic...

Published: 08/10/2019 | Inventor(s): Nicholas Greene, Andrew Copp

Keywords(s): Women's Health & Obstetrics

Category(s): Therapeutic